Study of laxative and hepatoprotective activity of extracts obtained from Prunus domestica fruits

The experimental work focused on the study of pharmacological properties extracts obtained from Prunus domestica fruits to create a prospective laxative drug with moderate hepatoprotective properties. fruit have been shown pronounced and effect. Extract containing fibers at dose 200 mg/kg was selected as most active extract for activity among all fruits. It conventionally named “Prunophyte”. Studies specific action “Prunophyte” in model comorbid functional constipation background combined alcoholic liver disease rats showed that had positive dynamics treatment subacute disease. In some cases it exceeded effects combination therapy drugs “Silibor” 25 “Senadexin” 14 mg/kg. extract, contrast “Senodexin”, did not cause signs diarrhea animals, which may be beneficial feature this subsequent clinical use. This has can promising alternative one-time complex herbal laxatives hepatoprotectors, will avoid polypragmatism conditions gastroenterology associated dysfunction.